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Index > Protein center > Micu1(Gene name) > Mouse
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  • Micu1 (Gene name),
  • Calcium uptake protein 1, mitochondrial (Protein name ),  MICU1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Micu1(Cbara1);
    Protein name:
    Calcium uptake protein 1, mitochondrial;
    Alternative:
    Calcium-binding atopy-related autoantigen 1 homolog;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with MCU.
    Function:
    Key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. May act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner.
    Subcellular Location:
    Mitochondrion inner membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    477
    Sequence:
    50:
    MFRLNTLSAL | AELAVGSRWY | HGASQPTQTK | RRLMLVAFLG | ASAVTASTGL | 
    100:
    LWKKAHAESP | PCVNSKKPDT | EDKERNKDSG | EVSSREGRAA | DAAAEPYPED | 
    150:
    KKKKRSGFRD | RKVMEYENRI | RAYSTPDKIF | RYFATLKVIN | EPGETEVFMT | 
    200:
    PQDFVRSITP | NEKQPEHLGL | DQYIIKRFDG | KKIAQEREKF | ADEGSIFYSL | 
    250:
    GECGLISFSD | YIFLTTVLST | PQRNFEIAFK | MFDLNGDGEV | DMEEFEQVQS | 
    300:
    IIRSQTSMGM | RHRDRPTTGN | TLKSGLCSAL | TTYFFGADLK | GKLTIKNFLE | 
    350:
    FQRKLQHDVL | KLEFERHDPV | DGRISERQFG | GMLLAYSGVQ | SKKLTAMQRQ | 
    400:
    LKKHFKDGKG | LTFQEVENFF | TFLKNINDVD | TALSFYHMAG | ASLDKVTMQQ | 
    450:
    VARTVAKVEL | SDHVCDVVFA | LFDCDGNGEL | SNKEFVSIMK | QRLMRGLEKP | 
    477:
    KDMGFTRLMQ | AMWKCAQETA | WDFALPK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    E15398h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    E15398r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    E15398b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    E15398m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    U15398b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    U15398h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    U15398m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    U15398r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    P15398Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    P15398Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Cat.:
    P15398Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
    Protein for Mouse Calcium uptake protein 1, mitochondrial
    Protein for Mouse Calcium uptake protein 1, mitochondrial
    Protein for Mouse Calcium uptake protein 1, mitochondrial
    Protein for Mouse Calcium uptake protein 1, mitochondrial

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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6J.
      tissue: Corpora quadrigemina.
      tissue: Embryo.
      tissue: Liver.
      tissue: Lung.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      strain: FVB/N.
      tissue: Eye.
      tissue: Mammary tumor.
      tissue: Salivary gland.
    3. 3.
      "A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter."
      De Stefani D. , Raffaello A. , Teardo E. , Szabo I. , Rizzuto R.
      Nature476:336-340(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    4. 4.
      "MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling."
      Plovanich M. , Bogorad R.L. , Sancak Y. , Kamer K.J. , Strittmatter L. , Li A.A. , Girgis H.S. , Kuchimanchi S. , De Groot J. , Speciner L. , Taneja N. , Oshea J. , Koteliansky V. , Mootha V.K.
      PLoS ONE8:E55785-E55785(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH MCU AND MICU2;TISSUE SPECIFICITY
    5. 5.
      "MICU1 and MICU2 finely tune the mitochondrial Ca(2+) uniporter by exerting opposite effects on MCU activity."
      Patron M. , Checchetto V. , Raffaello A. , Teardo E. , Vecellio Reane D. , Mantoan M. , Granatiero V. , Szabo I. , De Stefani D. , Rizzuto R.
      Mol. Cell53:726-737(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MICU2;DISULFIDE BOND;CALCIUM-BINDING MUTAGENESIS OF CYS-62; CYS-203; ASP-233; GLU-244; CYS-277; ASP-423; GLU-434 AND CYS-465
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