Gene name:
Micu1 (Cbara1) ;
Protein name:
Calcium uptake protein 1, mitochondrial ;
Alternative:
Calcium-binding atopy-related autoantigen 1 homolog ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with MCU.
Function:
Key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. May act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner.
Subcellular Location:
Mitochondrion inner membrane
Single-pass membrane protein
Protein Attributes:
50:
MFRLNTLSAL | AELAVGSRWY | HGASQPTQTK | RRLMLVAFLG | ASAVTASTGL |
100:
LWKKAHAESP | PCVNSKKPDT | EDKERNKDSG | EVSSREGRAA | DAAAEPYPED |
150:
KKKKRSGFRD | RKVMEYENRI | RAYSTPDKIF | RYFATLKVIN | EPGETEVFMT |
200:
PQDFVRSITP | NEKQPEHLGL | DQYIIKRFDG | KKIAQEREKF | ADEGSIFYSL |
250:
GECGLISFSD | YIFLTTVLST | PQRNFEIAFK | MFDLNGDGEV | DMEEFEQVQS |
300:
IIRSQTSMGM | RHRDRPTTGN | TLKSGLCSAL | TTYFFGADLK | GKLTIKNFLE |
350:
FQRKLQHDVL | KLEFERHDPV | DGRISERQFG | GMLLAYSGVQ | SKKLTAMQRQ |
400:
LKKHFKDGKG | LTFQEVENFF | TFLKNINDVD | TALSFYHMAG | ASLDKVTMQQ |
450:
VARTVAKVEL | SDHVCDVVFA | LFDCDGNGEL | SNKEFVSIMK | QRLMRGLEKP |
477:
KDMGFTRLMQ | AMWKCAQETA | WDFALPK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
ELISA Kit for Mouse Calcium uptake protein 1, mitochondrial
CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
CLIA Kit for Mouse Calcium uptake protein 1, mitochondrial
Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Polyclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Monoclonal Antibody for Mouse Calcium uptake protein 1, mitochondrial
Protein for Mouse Calcium uptake protein 1, mitochondrial
Protein for Mouse Calcium uptake protein 1, mitochondrial
Protein for Mouse Calcium uptake protein 1, mitochondrial
Protein for Mouse Calcium uptake protein 1, mitochondrial
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Corpora quadrigemina .
tissue :
Embryo .
tissue :
Liver .
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
strain :
FVB/N .
tissue :
Eye .
tissue :
Mammary tumor .
tissue :
Salivary gland .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
4.
"MICU2, a paralog of MICU1, resides within the mitochondrial uniporter complex to regulate calcium handling."
Plovanich M.
,
Bogorad R.L.
,
Sancak Y.
,
Kamer K.J.
,
Strittmatter L.
,
Li A.A.
,
Girgis H.S.
,
Kuchimanchi S.
,
De Groot J.
,
Speciner L.
,
Taneja N.
,
Oshea J.
,
Koteliansky V.
,
Mootha V.K.
PLoS ONE8:E55785-E55785(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN A COMPLEX WITH MCU AND MICU2;TISSUE SPECIFICITY
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH MICU2;DISULFIDE BOND;CALCIUM-BINDING MUTAGENESIS OF CYS-62; CYS-203; ASP-233; GLU-244; CYS-277; ASP-423; GLU-434 AND CYS-465